001), and the bias and precision were -0.19 ± 1.58 mm Hg. The correlations between the ventilator and the volumetric CO2 monitor for PĒCO2 were r = 0.96 and r(2) = 0.92 (P <. 001), and the bias and precision were 0.02 ± 0.04. For VD/VT the correlations were r = 0.95 and r(2) = 0.91 (P <. The correlations, bias, and precision between the ventilator and metabolic analyzer measurements for PĒCO2 were r = 0.97, r(2) = 0.93 (P <. There was a strong agreement between ventilator derived measurements and metabolic analyzer or volumetric CO2 monitor measurements of PĒCO2 and VD/VT. Thirty-one ventilator derived measurements were compared to measurements using 3 different metabolic analyzers, and 36 ventilator derived measurements were compared to measurements from a volumetric CO2 monitor. We calculated PĒCO2 and VD/VT from ventilator derived volumetric CO2 measurements of VCO2 and compared them to metabolic analyzer and volumetric CO2 monitor measurements.Ī total of 67 measurements in 36 subjects recovering from acute lung injury or ARDS were compared. The Dräger XL ventilator is equipped with integrated volumetric CO2 monitoring and calculates minute CO2 production (VCO2). Calculation of physiologic dead space (dead space divided by tidal volume ) using the Enghoff modification of the Bohr equation requires measurement of the partial pressure of mean expired CO2 (PĒCO2) by exhaled gas collection and analysis, use of a metabolic analyzer, or use of a volumetric CO2 monitor.

Calculate physiological dead space